Animal reproduction studies haven't been performed with the drug blend-promethazine and codeine. It's not recognized whether this drug mixture could potentially cause fetal harm when administered to a Expecting woman or can have an impact on reproduction ability.

Hyperexcitability and irregular movements are already reported in patients pursuing a single administration of promethazine HCl. Thing to consider needs to be presented for the discontinuation of promethazine HCl also to using other medicine if these reactions take place.

Lively and prophylactic procedure of movement sickness. Antiemetic therapy in postoperative people.

Caution need to be exercised when promethazine hydrochloride and codeine phosphate syrup is administered to some nursing lady.

When specified concomitantly with Promethazine HCl Oral Answer, the dose of barbiturates must be minimized by a minimum of 1-50 percent, as well as dose of narcotics needs to be diminished by one particular-quarter to at least one-50 percent. Dosage need to be individualized. Too much quantities of Promethazine HCl relative into a narcotic could bring on restlessness and motor hyperactivity in the affected individual with agony; these indications ordinarily disappear with sufficient Charge of the soreness.

A pharmacist can advocate an suitable measuring system and can provide Recommendations for measuring the correct dose.

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are pregnant or approach to become Expecting. Promethazine Hydrochloride and Codeine Phosphate Oral Remedy can harm your unborn toddler. See “What's the most important information and facts I need to learn about Promethazine Hydrochloride and Codeine Phosphate Oral Alternative?” are breastfeeding or decide to breastfeed. Codeine passes into your breast milk and may cause major Unintended effects as part of your toddler which includes improved sleepiness, respiration problems (respiratory depression), and Demise. It's not known if promethazine can move into your breast milk.

two) Area the mixture inside a sealable bag, empty can, or other container to prevent the drug from leaking or breaking outside of a garbage bag, or to dispose of in accordance with nearby point out rules and/or restrictions.

Consideration really should be provided into the discontinuation of promethazine HCl and to the usage of other drugs if these reactions website come about. Respiratory depression, nightmares, delirium, and agitated conduct have also been claimed in some of these clients.

In Gals with typical codeine metabolism (typical CYP2D6 action), the level of codeine secreted into human milk is small and dose-dependent. There isn't any info on the results with the codeine on milk output.

Because of inconsistencies involving the drug labels on DailyMed and also the capsule images supplied by RxImage, we no more Show the RxImage pill visuals connected with drug labels.

Actual physical dependence, the affliction by which ongoing administration on the drug is required to prevent the looks of a withdrawal syndrome, assumes clinically significant proportions only just after many months of continued oral opioid use, Whilst some delicate degree of Bodily dependence could produce right after a couple of days of opioid therapy.